Cebpa^m4443Dajl
Chemically induced Allele Detail

Summary

• Symbol: Cebpa^m4443Dajl
• Name: CCAAT/enhancer binding protein alpha; mutation 4443 David J Lloyd
• MGI ID: MGI:3848341
• Synonyms: Cebpa^I68N, Cebpa^m
• Gene: Cebpa Location: Chr7:34818718-34821353 bp, + strand Genetic Position: Chr7, 21.02 cM
• Alliance: Cebpa^m4443Dajl page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis produced a pedigree line 4443 with a T to A transversion that results in an amino acid substitution of isoleucine to asparagine at position 68 (I68N). Additional mutations may reside between rs3142560 and Cebpa. (J:149088)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cebpa Mutation: 16 strains or lines available

References

• Original: J:149088 Juan T, et al., Identification of three loci affecting HDL-cholesterol levels in a screen for chemically induced recessive mutations in mice. J Lipid Res. 2009 Mar;50(3):534-45
• All: 1 reference(s)