Lrrc4^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Lrrc4^tm1Lex
• Name: leucine rich repeat containing 4; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:3848335
• Synonyms: NGL-2^-
• Gene: Lrrc4 Location: Chr6:28828125-28831746 bp, - strand Genetic Position: Chr6, 12.05 cM
• Alliance: Lrrc4^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:149048
• Parent Cell Line: Lex-2 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding exon was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on brain extracts. (J:149048)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Lrrc4 Mutation: 28 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:149048 Zhang W, et al., Netrin-G2 and netrin-G2 ligand are both required for normal auditory responsiveness. Genes Brain Behav. 2008 Jun;7(4):385-92
• All: 6 reference(s)