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Tg(SMN2*)1951Ahmb
Transgene Detail
Nomenclature
Symbol: Tg(SMN2*)1951Ahmb
Name: transgene insertion 1951, Arthur H M Burghes
MGI ID: MGI:3847329
Synonyms: line 1951, SMN(VDQNQKE)
Transgene: Tg(SMN2*)1951Ahmb  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe transgenic construct encodes a truncated form of SMN2 (exons 1-6) with the added motif VDQNQKE under control of a 4.1 kb SMN2 promoter. Ten founder lines were obtained and lines 1946, 1947, and 1951 (which received more characterization) were established. (J:148541)
Phenotypes
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Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:148541 Workman E, et al., A SMN missense mutation complements SMN2 restoring snRNPs and rescuing SMA mice. Hum Mol Genet. 2009 Jun 15;18(12):2215-29
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory