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Transgene Detail
Symbol: Tg(CAG-luc,-GFP)L2G85Chco
Name: transgene insertion L2G85, Christopher H Contag
MGI ID: MGI:3844218
Synonyms: L2685, L2G85, luc+, Tg (CAG- Luc, GFP)
Transgene: Tg(CAG-luc,-GFP)L2G85Chco  Location: unknown  Genetic Position: Chr7, Syntenic
Strain of Origin:  FVB
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
Mutation detailsA transgenic construct containing a modified firefly luciferase gene open reading frame, 54bp of the foot and mouth disease virus (FMDV) 2A sequence (ribsome slippage site) and eGFP sequence under the control of the chicken beta actin promoter coupled with the cytomegalovirus (CMV) immediate early enhancer (CAG), was injected into fertilized FVB mouse eggs. Founder line L2G85 animals were bred to wildtype FVB mice. (J:137739, J:148234)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 6 strains available      Cell Lines: 0 lines available
Fine mapping performed at The Jackson Laboratory indicates that the transgene integrated onto the proximal end of Chr. 7 and the congenic interval extends from D7Mit306 (10 Mb) through D7Jmp8 (29 Mb).
Original:  J:148234 Cao YA, et al., Shifting foci of hematopoiesis during reconstitution from single stem cells. Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):221-6
All:  35 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.17
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