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Tg(Hspa2-cre)1Eddy
Transgene Detail
Nomenclature
Symbol: Tg(Hspa2-cre)1Eddy
Name: transgene insertion 1, Edward M Eddy
MGI ID: MGI:3843498
Synonyms: Hspa2cre, Hspa2-cre, Hspa2-cre line 54
Transgene: Tg(Hspa2-cre)1Eddy  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsThe Hspa2-Cre transgene was designed with (from 5' to 3') a 53 bp mouse Acrv1 (acrosomal vesicle protein 1 [SP-10]) insulator element, a promoter element from the mouse Hspa2 locus (heat shock protein 2 [Hsp70-2]); containing the ATG start site and 892 bp of immediately upstream sequence), a 275 bp fragment of the cre gene, the bovine growth hormone 3' UTR and polyA sequence, and another 53 bp mouse Acrv1 insulator element. This transgene was injected into C57BL/6 pronuclear stage embryos. Expression of Cre recombinase is directed to the developing male germ cells. (J:148085, J:156314)
Recombinase
activity
Activity:
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Driver: Hspa2     Summary of all recombinase alleles driven by Hspa2. Comparative matrix view of recombinase activities
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:156314 Inselman AL, et al., Heat shock protein 2 promoter drives cre expression in spermatocytes of transgenic mice. Genesis. 2010 Feb;48(2):114-20
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory