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Slc3a2tm1.1Mgin
Targeted Allele Detail
Nomenclature
Symbol: Slc3a2tm1.1Mgin
Name: solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2; targeted mutation 1, Mark H Ginsberg
MGI ID: MGI:3843272
Synonyms: Slc3a2f
Gene: Slc3a2  Location: Chr19:8706882-8723369 bp, - strand  Genetic Position: Chr19, 5.44 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:134813
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExons 1 and 2 were floxed and an frt flanked neo cassette was inserted in intron 2 via homologous recombination. The neo cassette was then removed by Flp mediated recombination. (J:134813)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc3a2 Mutation:  13 strains or lines available
References
Original:  J:134813 Feral CC, et al., CD98hc (SLC3A2) participates in fibronectin matrix assembly by mediating integrin signaling. J Cell Biol. 2007 Aug 13;178(4):701-11
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/04/2020
MGI 6.14
The Jackson Laboratory