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Dclre1ctm1Jsek
Targeted Allele Detail
Nomenclature
Symbol: Dclre1ctm1Jsek
Name: DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae); targeted mutation 1, JoAnn Sekiguchi
MGI ID: MGI:3843046
Synonyms: Artemis-P70, ArtP70
Gene: Dclre1c  Location: Chr2:3424131-3464130 bp, + strand  Genetic Position: Chr2, 1.93 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:147864
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted
Mutations:    Insertion, Nucleotide substitutions
 
Mutation details
Generation of the Dclre1ctm1Jsek allele
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dclre1c Mutation:  6 strains or lines available
References
Original:  J:147864 Huang Y, et al., Impact of a hypomorphic Artemis disease allele on lymphocyte development, DNA end processing, and genome stability. J Exp Med. 2009 Apr 13;206(4):893-908
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory