About   Help   FAQ
Achetm4.1Pata
Targeted Allele Detail
Nomenclature
Symbol: Achetm4.1Pata
Name: acetylcholinesterase; targeted mutation 4.1, Palmer Taylor
MGI ID: MGI:3842445
Synonyms: AChEdel E5 + 6
Gene: Ache  Location: Chr5:137287519-137294466 bp, + strand  Genetic Position: Chr5, 76.32 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:147855
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 5 and 6 were replaced with a floxed neo cassette, which was subsequently removed by germ line, cre mediated recombination. Ache serum activity is nearly double of that in wild-type mice. (J:147855)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ache Mutation:  11 strains or lines available
References
Original:  J:147855 Camp S, et al., Acetylcholinesterase (AChE) gene modification in transgenic animals: functional consequences of selected exon and regulatory region deletion. Chem Biol Interact. 2005 Dec 15;157-158:79-86
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/15/2017
MGI 6.10
The Jackson Laboratory