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Achetm4Pata
Targeted Allele Detail
Nomenclature
Symbol: Achetm4Pata
Name: acetylcholinesterase; targeted mutation 4, Palmer Taylor
MGI ID: MGI:3842444
Synonyms: AChE del E5+6-, AChEdel E5 + 6/Neo
Gene: Ache  Location: Chr5:137287519-137294466 bp, + strand  Genetic Position: Chr5, 76.32 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:147855
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 5 and 6 were replaced with a floxed neo cassette. Ache serum activity is dramatically reduced compared to in wild-type mice. (J:147855)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ache Mutation:  10 strains or lines available
References
Original:  J:147855 Camp S, et al., Acetylcholinesterase (AChE) gene modification in transgenic animals: functional consequences of selected exon and regulatory region deletion. Chem Biol Interact. 2005 Dec 15;157-158:79-86
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory