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Rspo2tm1Suda
Targeted Allele Detail
Nomenclature
Symbol: Rspo2tm1Suda
Name: R-spondin 2; targeted mutation 1, Toshio Suda
MGI ID: MGI:3839444
Gene: Rspo2  Location: Chr15:43020811-43170818 bp, - strand  Genetic Position: Chr15, 16.73 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:146829
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 145 bp fragment of exon 2 was replaced with a neo cassette via homologous recombination. RT-PCR confirmed the absence of RNA expression in lungs from homozygous embryos. (J:146829)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rspo2 Mutation:  7 strains or lines available
References
Original:  J:146829 Yamada W, et al., Craniofacial malformation in R-spondin2 knockout mice. Biochem Biophys Res Commun. 2009 Apr 10;381(3):453-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory