Tg(TCF/Lef1-cre/ERT2)1Dje
Transgene Detail

Summary

• Symbol: Tg(TCF/Lef1-cre/ERT2)1Dje
• Name: transgene insertion 1, Douglas J Epstein
• MGI ID: MGI:3836892
• Synonyms: Tg(Fos-cre/ERT2)1Dje, TopCreERT2
• Transgene: Tg(TCF/Lef1-cre/ERT2)1Dje Location: unknown
• Alliance: Tg(TCF/Lef1-cre/ERT2)1Dje page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(TCF/Lef1-cre/ERT2)1Dje expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Fos

• Mutation details: Three consensus LEF/TCF-binding motifs upstream of a minimal Fos promoter were used to drive the expression of a tamoxifen-inducible cre construct. (J:99408)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Fos (species not specified) Summary of all recombinase alleles driven by Fos. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:99408 Riccomagno MM, et al., Wnt-dependent regulation of inner ear morphogenesis is balanced by the opposing and supporting roles of Shh. Genes Dev. 2005 Jul 1;19(13):1612-23
• All: 3 reference(s)