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Fgfr1Eask
Spontaneous Allele Detail
Nomenclature
Symbol: Fgfr1Eask
Name: fibroblast growth factor receptor 1; ear askew
MGI ID: MGI:3836281
Gene: Fgfr1  Location: Chr8:25518759-25575718 bp, + strand  Genetic Position: Chr8, 14.12 cM
Abnormal ear position and shape in Fgfr1Eask/Fgfr1+ mice (right) and wild-type littermates (left)

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  BALB/cByJ-Agtpbp1pcd-3J/J
Mutation
description
Allele Type:    Spontaneous
Mutation:    Single point mutation
 
Mutation detailsThis spontaneous point mutation is a C-to-G transversion at position 25,557,813 (GRCm38) that results in an asparagine to lysine substitution at amino acid 147 (p.N147K). (J:179274, J:222308)
Inheritance:    Dominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fgfr1 Mutation:  170 strains or lines available
References
Original:  J:179274 Kane C, et al., An ear pinna mutation in Fgfr1. MGI Direct Data Submission. 2012;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/07/2020
MGI 6.15
The Jackson Laboratory