N4bp1^tm1.1Mku
Targeted Allele Detail

Summary

• Symbol: N4bp1^tm1.1Mku
• Name: NEDD4 binding protein 1; targeted mutation 1.1, Michael R Kuehn
• MGI ID: MGI:3836056
• Gene: N4bp1 Location: Chr8:87567764-87612489 bp, - strand Genetic Position: Chr8, 42.1 cM
• Alliance: N4bp1^tm1.1Mku page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:143823
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Germ line, cre mediated recombination was used to remove exon 2 from a floxed allele. (J:143823)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any N4bp1 Mutation: 46 strains or lines available

References

• Original: J:143823 Oberst A, et al., The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch. Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11280-5
• All: 1 reference(s)