Vsx2^tm2.1Kash
Targeted Allele Detail

Summary

• Symbol: Vsx2^tm2.1Kash
• Name: visual system homeobox 2; targeted mutation 2.1, Kamal Sharma
• MGI ID: MGI:3835964
• Synonyms: Chx10::CFP
• Gene: Vsx2 Location: Chr12:84616602-84642231 bp, + strand Genetic Position: Chr12, 39.28 cM
• Alliance: Vsx2^tm2.1Kash page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:145621
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Germ line, cre mediated recombination was used to remove the floxed STOP cassette. CFP is expressed in V2a interneurons. (J:145621)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vsx2 Mutation: 28 strains or lines available

References

• Original: J:145621 Crone SA, et al., Genetic ablation of V2a ipsilateral interneurons disrupts left-right locomotor coordination in mammalian spinal cord. Neuron. 2008 Oct 9;60(1):70-83
• All: 4 reference(s)