Tg(Scgb1a1-IL11)2-12Eli
Transgene Detail

Summary

• Symbol: Tg(Scgb1a1-IL11)2-12Eli
• Name: transgene insertion 2-12, Jack A Elias
• MGI ID: MGI:3835847
• Synonyms: CC10-IL-11 Tg
• Transgene: Tg(Scgb1a1-IL11)2-12Eli Location: unknown
• Alliance: Tg(Scgb1a1-IL11)2-12Eli page

Transgene origin

• Strain of Origin: (CBA x C57BL/6)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Scgb1a1-IL11)2-12Eli expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  IL11 (3589)

  Il11	(MGI:107613)

• Mutation details: The rat CC10 promoter was used to target the expression of human IL-11 to airway tissues. In addition to line 2-12, line 3-2 was also generated. (J:128758)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:128758 Tang W, et al., Targeted expression of IL-11 in the murine airway causes lymphocytic inflammation, bronchial remodeling, and airways obstruction. J Clin Invest. 1996 Dec 15;98(12):2845-53
• All: 5 reference(s)