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Cldn6tm1(cre)Dkwu
Targeted Allele Detail
Nomenclature
Symbol: Cldn6tm1(cre)Dkwu
Name: claudin 6; targeted mutation 1, Doris Wu
MGI ID: MGI:3834897
Synonyms: Claudin6-cre
Gene: Cldn6  Location: Chr17:23679348-23682446 bp, + strand  Genetic Position: Chr17, 11.99 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:145443
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was use to replace the only exon of the gene with an inserted cre coding sequence. (J:145443)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cldn6     Summary of all recombinase alleles driven by Cldn6. Comparative matrix view of recombinase activities
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 8 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cldn6 Mutation:  7 strains or lines available
References
Original:  J:145443 Wu D, Generation of a cre knock-in allele of Cldn6. MGI Direct Data Submission. 2009;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/13/2021
MGI 6.16
The Jackson Laboratory