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Tg(Ly6a-BCR/ABL1)IS1AIsg
Transgene Detail
Summary
Symbol: Tg(Ly6a-BCR/ABL1)IS1AIsg
Name: transgene insertion IS1A, Isidro Sanchez-Garcia
MGI ID: MGI:3834461
Synonyms: IS1A
Transgene: Tg(Ly6a-BCR/ABL1)IS1AIsg  Location: unknown  
Alliance: Tg(Ly6a-BCR/ABL1)IS1AIsg page
Transgene
origin
Strain of Origin:  (CBA x C57BL/6J)
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Ly6a-BCR/ABL1)IS1AIsg expresses 2 genes
 
Mutation detailsThe promoter was used to drive hematopoietic stem cell-specific expression of a human BCR-ABL1p210 fusion. Two lines were created (IS1A and IS1B) that exhibit similar phenotypes. (J:144382)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:144382 Perez-Caro M, et al., Cancer induction by restriction of oncogene expression to the stem cell compartment. EMBO J. 2009 Jan 7;28(1):8-20
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory