About   Help   FAQ
Targeted Allele Detail
Symbol: Gng7tm2(cre/PGR)Mmsh
Name: guanine nucleotide binding protein (G protein), gamma 7; targeted mutation 2, Masayoshi Mishina
MGI ID: MGI:3833956
Synonyms: Gng7mCrePR
Gene: Gng7  Location: Chr10:80948624-81014945 bp, - strand  Genetic Position: Chr10, 39.72 cM
Ablation of medium-spiny projection neurons in the striatum of Gng7tm2(cre/PGR)Mmsh/Gng7+ Eno2tm1(DTA)Hsak/Eno2+ mice

Show the 1 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:145152
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    mifepristone
Mutation:    Insertion
Mutation detailsAn inducible cre cassette consisting of mammalian optimized cre fused to the human progesterone receptor followed by a neo selection cassette in the inverse orientation were inserted into the translation initiation site via homologous recombination. Following RU-496 treatment no Cre activity was detected in brain slices. (J:145152)
Generation of the Gng7tm1(cre)Mmsh and Gng7tm2(cre/PGR)Mmsh alleles
 Tissue activity of this recombinase allele
Driver: Gng7     Summary of all recombinase alleles driven by Gng7. Comparative matrix view of recombinase activities

View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gng7 Mutation:  70 strains or lines available
Original:  J:145152 Kishioka A, et al., A novel form of memory for auditory fear conditioning at a low-intensity unconditioned stimulus. PLoS One. 2009;4(1):e4157
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.12
The Jackson Laboratory