Tg(EF1A-GDNF)S6Hasa
Transgene Detail

Summary

• Symbol: Tg(EF1A-GDNF)S6Hasa
• Name: transgene insertion S6, Hannu Sariola
• MGI ID: MGI:3833747
• Transgene: Tg(EF1A-GDNF)S6Hasa Location: unknown
• Alliance: Tg(EF1A-GDNF)S6Hasa page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The promoter was used to drive testis-specific expression of the human cDNA. Four founders were created (males: C10 and C12; females: S6 and E19) with 10, 3, 20, and 4 copies of the transgene respectively. Male founders are sterile and line S6 was selected as the representative line. (J:60721)

Tumor Data

List all tumor models in MMHCdb carrying Tg(EF1A-GDNF)S6Hasa

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:60721 Meng X, et al., Regulation of cell fate decision of undifferentiated spermatogonia by GDNF. Science. 2000 Feb 25;287(5457):1489-93
• All: 1 reference(s)