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Tg(Pdgfra-cre/ERT2)1Wdr
Transgene Detail
Nomenclature
Symbol: Tg(Pdgfra-cre/ERT2)1Wdr
Name: transgene insertion 1, William D Richardson
MGI ID: MGI:3832569
Synonyms: Pdgra-creERT2, PRalphaBAC-CreER, Tg(Pdgra-cre/ERT2)1Wdr
Transgene: Tg(Pdgfra-cre/ERT2)1Wdr  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Mutation detailsA mouse PAC clone (RPCI21-546M3) containing the Pdgfra gene was modified by the insertion of a tamoxifen inducible cre recombinase gene into exon 2 together with an frt flanked chloramphenicol selection cassette that was subsequently excised. Eleven founders were produced, only two of which expressed cre as expected. The more strongly expressing transgene line is used as thge representative. (J:144591)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pdgfra     Summary of all recombinase alleles driven by Pdgfra. Comparative matrix view of recombinase activities
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:144591 Rivers LE, et al., PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice. Nat Neurosci. 2008 Dec;11(12):1392-401
All:  34 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory