About   Help   FAQ
Prlhtm1Taon
Targeted Allele Detail
Nomenclature
Symbol: Prlhtm1Taon
Name: prolactin releasing hormone; targeted mutation 1, Tatsushi Onaka
MGI ID: MGI:3832409
Gene: Prlh  Location: Chr1:90953108-90954027 bp, + strand  Genetic Position: Chr1, 45.81 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:144729
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsA 2 kb fragment including both exons 1 and 2 was replaced with a neo cassette via homologous recombination. RT-PCR and radioimmunoassay confirm the absence of RNA and protein expression in the hypothalamus and medulla oblongata of homozygous mice. (J:144729)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prlh Mutation:  0 strains or lines available
References
Original:  J:144729 Takayanagi Y, et al., Endogenous prolactin-releasing peptide regulates food intake in rodents. J Clin Invest. 2008 Dec;118(12):4014-24
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/17/2015
MGI 5.21
The Jackson Laboratory