mt-Tr^m2
Spontaneous Allele Detail

Nomenclature

• Symbol: mt-Tr^m2
• Name: mitochondrially encoded tRNA arginine; mutation 2
• MGI ID: MGI:3832223
• Synonyms: 9A
• Gene: mt-Tr Location: ChrMT:9808-9875 bp, + strand Genetic Position: ChrMT, Syntenic

Mutation origin

• Strain of Origin: various

Mutation description

• Allele Type: Spontaneous
• Mutation: Nucleotide repeat expansion
• The adenine repeat in the D stem is polymorphic with 9 adenines in this allele. (J:67312, J:97969)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 4 strains available Cell Lines: 0 lines available
• Carrying any mt-Tr Mutation: 10 strains or lines available

Notes

This polymorphism is present in ALR/Lt, NOD/ShiLtDvs, and SKH2/J. A variant with 10 adenines is found in A/J, ALS/Lt, NOD/ShiLtJ and NZB/B1NJ.

References

• Original: J:67312 Johnson KR, et al., A nuclear-mitochondrial DNA interaction affecting hearing impairment in mice. Nat Genet. 2001 Feb;27(2):191-4
• All: 2 reference(s)