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Targeted Allele Detail
Symbol: Kalrntm1.1Npl
Name: kalirin, RhoGEF kinase; targeted mutation 1.1, Neuropeptide Laboratory
MGI ID: MGI:3831292
Synonyms: Kal7KO, Kalrntm1.1Riem
Gene: Kalrn  Location: Chr16:33974258-34573532 bp, - strand  Genetic Position: Chr16, 24.27 cM
Germline Transmission:  Earliest citation of germline transmission: J:142364
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsGerm line, cre-mediated recombination was used to remove the exon specific for isoform 7. The absence of protein expression of Kalrn7 and deltaKalrn7 was confirmed by western blot analysis of cerebral cortex extracts. (J:142364)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kalrn Mutation:  109 strains or lines available
Original:  J:142364 Ma XM, et al., Kalirin-7 is required for synaptic structure and function. J Neurosci. 2008 Nov 19;28(47):12368-82
All:  5 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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