Tg(OPN1LW-EGFP)85933Hue
Transgene Detail

Summary

• Symbol: Tg(OPN1LW-EGFP)85933Hue
• Name: transgene insertion 85933, Thomas Hughes
• MGI ID: MGI:3831094
• Synonyms: R6.85933
• Transgene: Tg(OPN1LW-EGFP)85933Hue Location: unknown Genetic Position: Chr10, Syntenic
• Alliance: Tg(OPN1LW-EGFP)85933Hue page

Transgene origin

• Strain of Origin: (C57BL/6J x SJL)F1

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The transgene comprises 6.8 kb of human genomic DNA containing the 5' regulatory sequence of the human opsin 1 (cone pigments), long-wave-sensitive (red cone photoreceptor pigment) gene joined to the coding sequence for enhanced green fluorescent protein followed by a Myc epitope tag and an intron and polyadenylation signal from SV40. Transgenic mice exhibit green fluorescence specifically of cone cells of the visual retina. In this transgenic line, EGFP-expressing cells reproducibly constitute a small proportion of cone cells in the ventral retina and the majority of dorsal retinal cone cells. (J:144387, J:175509)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:144387 Fei Y, et al., Transgenic expression of the jellyfish green fluorescent protein in the cone photoreceptors of the mouse. Vis Neurosci. 2001 Jul-Aug;18(4):615-23
• All: 7 reference(s)