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Tgfbitm1Zhao
Targeted Allele Detail
Nomenclature
Symbol: Tgfbitm1Zhao
Name: transforming growth factor, beta induced; targeted mutation 1, Yongliang Zhao
MGI ID: MGI:3830817
Gene: Tgfbi  Location: Chr13:56609603-56639339 bp, + strand  Genetic Position: Chr13, 30.09 cM, cytoband B-C1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:143036
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 4 through 6 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on mouse embryonic fibrolasts. (J:143036)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tgfbi Mutation:  1 strain or line available
References
Original:  J:143036 Zhang Y, et al., TGFBI deficiency predisposes mice to spontaneous tumor development. Cancer Res. 2009 Jan 1;69(1):37-44
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/25/2015
MGI 5.21
The Jackson Laboratory