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Rimbp3tm1Gxu
Targeted Allele Detail
Nomenclature
Symbol: Rimbp3tm1Gxu
Name: RIMS binding protein 3; targeted mutation 1, Guo-Liang Xu
MGI ID: MGI:3830663
Gene: Rimbp3  Location: Chr16:17208135-17213921 bp, + strand  Genetic Position: Chr16, 10.67 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:144218
Parent Cell Line:  MPI-II (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire sequence encoding the SbcC domain was replaced with a PGK-neo cassette via homologous recombination. Western blot analysis confirmed the absnece of protein in testes from homozygous mice. (J:144218)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rimbp3 Mutation:  17 strains or lines available
References
Original:  J:144218 Zhou J, et al., RIM-BP3 is a manchette-associated protein essential for spermiogenesis. Development. 2009 Feb;136(3):373-82
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory