Tg(CMV-PRKR)1Wcl
Transgene Detail

Summary

• Symbol: Tg(CMV-PRKR)1Wcl
• Name: transgene insertion 1, Warren C Ladiges
• MGI ID: MGI:3830478
• Synonyms: Tg(CMV-EIF2AK2)1Wcl, Tg(CMV-PRKR)1Wcl
• Transgene: Tg(CMV-PRKR)1Wcl Location: unknown
• Alliance: Tg(CMV-PRKR)1Wcl page

Transgene origin

• Strain of Origin: (C57BL/6 x C3H)F1 x C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CMV-PRKR)1Wcl expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  EIF2AK2 (5610)

  Eif2ak2

  (MGI:1353449)

• Mutation details: cDNA encoding human eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2; previously PRKR, interferon-mediated double-stranded RNA-activated protein kinase) is expressed under control of a cytomegalovirus promoter. (J:143781)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:143781 Ladiges W, et al., Expression of human PKR protein kinase in transgenic mice. J Interferon Cytokine Res. 2002 Mar;22(3):329-34
• All: 1 reference(s)