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Tm7sf2tm1Fdp
Targeted Allele Detail
Nomenclature
Symbol: Tm7sf2tm1Fdp
Name: transmembrane 7 superfamily member 2; targeted mutation 1, Forbes D Porter
MGI ID: MGI:3829354
Synonyms: Dhcr14delta4-7
Gene: Tm7sf2  Location: Chr19:6062821-6068373 bp, - strand  Genetic Position: Chr19, 4.34 cM, cytoband A
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:143838
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAll sequence from intron 4 through intron 6 is replaced with a PGK-neomycin resistance cassette. Quantitative PCR confirmed the absence of expression. (J:143838)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tm7sf2 Mutation:  4 strains or lines available
References
Original:  J:143838 Wassif CA, et al., HEM dysplasia and ichthyosis are likely laminopathies and not due to 3beta-hydroxysterol Delta14-reductase deficiency. Hum Mol Genet. 2007 May 15;16(10):1176-87
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/12/2015
MGI 5.21
The Jackson Laboratory