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Targeted Allele Detail
Symbol: Gstt1tm1Kfuj
Name: glutathione S-transferase, theta 1; targeted mutation 1, Kazunori Fujimoto
MGI ID: MGI:3828088
Gene: Gstt1  Location: Chr10:75619647-75634418 bp, - strand  Genetic Position: Chr10, 38.58 cM, cytoband B5-C1
Germline Transmission:  Earliest citation of germline transmission: J:143552
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExons 1 and 2 were replaced with a neomycin resistance cassette. Mutant ES cell clone 9D5 was used to generate chimeric mice. No mRNA expression coulld be detected in the livers of homozygotes by RT-PCR. (J:143552)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gstt1 Mutation:  10 strains or lines available
Original:  J:143552 Fujimoto K, et al., Generation and functional characterization of mice with a disrupted glutathione S-transferase, theta 1 gene. Drug Metab Dispos. 2007 Dec;35(12):2196-202
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.17
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