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Cyb5atm1Wolf
Targeted Allele Detail
Nomenclature
Symbol: Cyb5atm1Wolf
Name: cytochrome b5 type A (microsomal); targeted mutation 1, C Roland Wolf
MGI ID: MGI:3826663
Synonyms: Cytb5lox
Gene: Cyb5a  Location: Chr18:84869463-84897996 bp, + strand  Genetic Position: Chr18, 57.53 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:143097
Parent Cell Line:  GK129 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA floxed neo cassette was inserted upstream of exon 2 and an additional site was inserted downstream of exon 5. (J:143097)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cyb5a Mutation:  15 strains or lines available
References
Original:  J:143097 Finn RD, et al., Defining the in Vivo Role for cytochrome b5 in cytochrome P450 function through the conditional hepatic deletion of microsomal cytochrome b5. J Biol Chem. 2008 Nov 14;283(46):31385-93
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory