Tspan33^tm1Stsa
Targeted Allele Detail

Summary

• Symbol: Tspan33^tm1Stsa
• Name: tetraspanin 33; targeted mutation 1, Schickwann Tsai
• MGI ID: MGI:3826388
• Synonyms: Pen^-
• Gene: Tspan33 Location: Chr6:29694221-29718558 bp, + strand Genetic Position: Chr6, 12.36 cM
• Alliance: Tspan33^tm1Stsa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:143158
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A section of DNA encoding part of the first and third transmembrane domains and all of the first extracellular domain and the second transmembrane domain was replaced witha self-excising cre-neo cassette. (J:143158)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tspan33 Mutation: 18 strains or lines available

References

• Original: J:143158 Heikens MJ, et al., Penumbra encodes a novel tetraspanin that is highly expressed in erythroid progenitors and promotes effective erythropoiesis. Blood. 2007 Apr 15;109(8):3244-52
• All: 1 reference(s)