Bptf^{Gt(A012C04)Wrst}
Gene trapped Allele Detail

Summary

• Symbol: Bptf^{Gt(A012C04)Wrst}
• Name: bromodomain PHD finger transcription factor; gene trap A012C04, Wolfgang Wurst
• MGI ID: MGI:3823037
• Synonyms: BPTF/FAC1^GT
• Gene: Bptf Location: Chr11:106923907-107022953 bp, - strand Genetic Position: Chr11, 70.11 cM
• Alliance: Bptf^{Gt(A012C04)Wrst} page

Mutation origin

• Mutant Cell Line: A012C04
• Germline Transmission: Earliest citation of germline transmission: J:142592
• Parent Cell Line: TBV2 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap vector pPT1betageo inserted after nucleotide 6627 of intron 1. RT-PCR analysis confirms the absence of wild-type mRNA expression and the presence of a LacZ containing fusion transcript. (J:142592)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Bptf Mutation: 157 strains or lines available

References

• Original: J:142592 Goller T, et al., Transcriptional regulator BPTF/FAC1 is essential for trophoblast differentiation during early mouse development. Mol Cell Biol. 2008 Nov;28(22):6819-27
• All: 1 reference(s)