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Tg(Myh7-Ptpn11)294Rbns
Transgene Detail
Nomenclature
Symbol: Tg(Myh7-Ptpn11)294Rbns
Name: transgene insertion 294, Jeffrey Robbins
MGI ID: MGI:3822135
Synonyms: beta-MHC-WT294
Transgene: Tg(Myh7-Ptpn11)294Rbns  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Myh7-Ptpn11)294Rbns expresses 1 gene
 
Mutation detailsThe promoter was used to drive expression of Ptpn11 in the fetal heart. Several lines were created and line 294 was used in subsequent experiments. (J:123963)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:123963 Nakamura T, et al., Mediating ERK 1/2 signaling rescues congenital heart defects in a mouse model of Noonan syndrome. J Clin Invest. 2007 Aug;117(8):2123-32
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory