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Targeted Allele Detail
Symbol: Ffar1tm1Dgen
Name: free fatty acid receptor 1; targeted mutation 1, Deltagen
MGI ID: MGI:3821733
Synonyms: GPR40 KO
Gene: Ffar1  Location: Chr7:30857390-30861564 bp, - strand  Genetic Position: Chr7, 19.25 cM
Germline Transmission:  Earliest citation of germline transmission: J:141957
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA 152 bp fragment corresponding to positions 143-294 of the open reading frame was replaced with a neomycin selection cassette. RT-PCR confirmed that mRNA was not produced. (J:141957)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ffar1 Mutation:  6 strains or lines available
Original:  J:141957 Lan H, et al., Lack of FFAR1/GPR40 does not protect mice from high-fat diet-induced metabolic disease. Diabetes. 2008 Nov;57(11):2999-3006
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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