About   Help   FAQ
Ffar1tm1Dgen
Targeted Allele Detail
Nomenclature
Symbol: Ffar1tm1Dgen
Name: free fatty acid receptor 1; targeted mutation 1, Deltagen
MGI ID: MGI:3821733
Synonyms: GPR40 KO
Gene: Ffar1  Location: Chr7:30857390-30861564 bp, - strand  Genetic Position: Chr7, 19.25 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:141957
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 152 bp fragment corresponding to positions 143-294 of the open reading frame was replaced with a neomycin selection cassette. RT-PCR confirmed that mRNA was not produced. (J:141957)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ffar1 Mutation:  5 strains or lines available
References
Original:  J:141957 Lan H, et al., Lack of FFAR1/GPR40 does not protect mice from high-fat diet-induced metabolic disease. Diabetes. 2008 Nov;57(11):2999-3006
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/16/2017
MGI 6.09
The Jackson Laboratory