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Tg(Cela1-cre/ERT2)1Stof
Transgene Detail
Nomenclature
Symbol: Tg(Cela1-cre/ERT2)1Stof
Name: transgene insertion 1, Doris A Stoffers
MGI ID: MGI:3820514
Synonyms: ElastaseCreERT2, Tg(Ela1-Cre/ESR1)1Stof
Transgene: Tg(Cela1-cre/ERT2)1Stof  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F1
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Mutation detailsA transgenic construct containing the rabbit Beta-globin (RBG) intron, a sequence encoding Cre/ESR1 (Cre recombinase fused to a mutant estrogen receptor ligand-binding domain (ERT2)) under the control of the acinar cell-specific rat elastase 1 (Cela1) promoter, and a rabbit Beta-globin polyadenylation cassette was made and injected into B6SJLF1 oocytes. (J:121254)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cela1     Summary of all recombinase alleles driven by Cela1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:121254 Desai BM, et al., Preexisting pancreatic acinar cells contribute to acinar cell, but not islet beta cell, regeneration. J Clin Invest. 2007 Apr;117(4):971-7
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/06/2021
MGI 6.16
The Jackson Laboratory