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Cd151tm1Mhe
Targeted Allele Detail
Nomenclature
Symbol: Cd151tm1Mhe
Name: CD151 antigen; targeted mutation 1, Martin E Hemler
MGI ID: MGI:3819817
Gene: Cd151  Location: Chr7:141467392-141471473 bp, + strand  Genetic Position: Chr7, 86.82 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:141595
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThis is a deletion that begins from a site in the 5' untranslated region, removes the first four coding exons and part of the fifth, and includes the first 168 amino acids (of 253). (J:141595)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd151 Mutation:  25 strains or lines available
References
Original:  J:141595 Takeda Y, et al., Deletion of tetraspanin Cd151 results in decreased pathologic angiogenesis in vivo and in vitro. Blood. 2007 Feb 15;109(4):1524-32
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory