Tg(tetO-GFP,-lacZ)G3Rsp
Transgene Detail

Summary

• Symbol: Tg(tetO-GFP,-lacZ)G3Rsp
• Name: transgene insertion G3, Rolf Sprengel
• MGI ID: MGI:3817960
• Synonyms: tetObi^lacZ/huGFP, Tg^GFPtetO7lacZ, TRE-LacZ/GFP
• Transgene: Tg(tetO-GFP,-lacZ)G3Rsp Location: unknown
• Alliance: Tg(tetO-GFP,-lacZ)G3Rsp page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA)F1

Transgene description

• Transgene Type: Transgenic (Inducible, Reporter)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: A TetO flanked by two CMV promoters in opposite orientations was used to drive lacZ and GFP expression. In the presence of tTA, intense expression is seen in the cortex, olfactory system, limbic lobe, and basal ganglia. Expression is weak in the thalamus, pontine and medullary structures, the spinal cord, and the eye. (J:141213)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:141213 Krestel HE, et al., A GFP-equipped bidirectional expression module well suited for monitoring tetracycline-regulated gene expression in mouse. Nucleic Acids Res. 2001 Apr 1;29(7):E39
• All: 9 reference(s)