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Tg(tetO-GFP,-lacZ)G3Rsp
Transgene Detail
Nomenclature
Symbol: Tg(tetO-GFP,-lacZ)G3Rsp
Name: transgene insertion G3, Rolf Sprengel
MGI ID: MGI:3817960
Synonyms: TgGFPtetO7lacZ, TRE-LacZ/GFP
Transgene: Tg(tetO-GFP,-lacZ)G3Rsp  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA)F1
Transgene
description
Transgene Type:    Transgenic (Inducible, Reporter)
Mutation:    Insertion
 
Mutation detailsA TetO flanked by two CMV promoters in opposite orientations was used to drive lacZ and GFP expression. In the presence of tTA, intense expression is seen in the cortex, olfactory system, limbic lobe, and basal ganglia. Expression is weak in the thalamus, pontine and medullary structures, the spinal cord, and eye. (J:141213)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:141213 Krestel HE, et al., A GFP-equipped bidirectional expression module well suited for monitoring tetracycline-regulated gene expression in mouse. Nucleic Acids Res. 2001 Apr 1;29(7):E39
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory