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Targeted Allele Detail
Symbol: Hoxa11tm1Dmwe
Name: homeobox A11; targeted mutation 1, Deneen M Wellik
MGI ID: MGI:3814861
Synonyms: Hoxa11eGFP
Gene: Hoxa11  Location: Chr6:52219086-52222790 bp, - strand  Genetic Position: Chr6, 25.4 cM
Germline Transmission:  Earliest citation of germline transmission: J:140709
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsAn eGFP construct was inserted 18 bp downstream of the start site in exon 1 replacing most of exon 1. This was followed by an SV40 T-antigen stop sequence and a self-excising neo cassette in reverse orientation. Cre mediated excision of the neo cassette occurs in the testes. (J:140709)
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 129 assay results
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Hoxa11 Mutation:  7 strains or lines available
Original:  J:140709 Nelson LT, et al., Generation and expression of a Hoxa11eGFP targeted allele in mice. Dev Dyn. 2008 Nov;237(11):3410-6
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory