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Tg(H2-K-Fosl2,EGFP)13Wag
Transgene Detail
Nomenclature
Symbol: Tg(H2-K-Fosl2,EGFP)13Wag
Name: transgene insertion 13, Erwin F Wagner
MGI ID: MGI:3813493
Synonyms: fra-2tg
Transgene: Tg(H2-K-Fosl2,EGFP)13Wag  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6 x CBA
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(H2-K-Fosl2,EGFP)13Wag expresses 1 gene
 
Mutation detailsThe ubiquitous H2-Kb promoter was used to drive expression of the cDNA encoding Fosl2 followed by an IRES-EGFP. Three founders were identified (12, 13 and 15). Lines 12 and 13 display the same phenotype while founder 15 failed to express thetransgene. Line 13 was used in subsequent analysis. (J:139032)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:139032 Eferl R, et al., Development of pulmonary fibrosis through a pathway involving the transcription factor Fra-2/AP-1. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10525-30
All:  5 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory