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Dmrt3tm1(KOMP)Vlcg
Targeted Allele Detail
Summary
Symbol: Dmrt3tm1(KOMP)Vlcg
Name: doublesex and mab-3 related transcription factor 3; targeted mutation 1, Velocigene
MGI ID: MGI:3812826
Synonyms: Dmrt3tm1Vlcg
Gene: Dmrt3  Location: Chr19:25587665-25601285 bp, + strand  Genetic Position: Chr19, 20.5 cM
Alliance: Dmrt3tm1(KOMP)Vlcg page
IMPC: Dmrt3 gene page
Mutation
origin
Mutant Cell Lines:  11087A-H3, 11087C-B1, 11087C-B11, 11087C-C11
Germline Transmission:  Earliest citation of germline transmission: J:203109
Parent Cell Line:  VGB6 (ES Cell)
Strain of Origin:  C57BL/6NTac
Project Collection: KOMP-Regeneron
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1
 
Mutation detailsThe insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 12422bp between positions 25588166-25600587 of Chromosome 19 (Build GRCm39). (J:136110)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Dmrt3 Mutation:  12 strains or lines available
Notes
Cell line 11087C-C11 was successfully used to make chimeric mice. Germline transmission was accomplished. J:203109
References
Original:  J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory