Lmod2tm1(KOMP)Vlcg
Targeted Allele Detail
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Symbol: |
Lmod2tm1(KOMP)Vlcg |
Name: |
leiomodin 2 (cardiac); targeted mutation 1, Velocigene |
MGI ID: |
MGI:3812792 |
Synonyms: |
Lmod2tm1Vlcg |
Gene: |
Lmod2 Location: Chr6:24597770-24605413 bp, + strand Genetic Position: Chr6, 11.28 cM, cytoband A3
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Alliance: |
Lmod2tm1(KOMP)Vlcg page
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IMPC: |
Lmod2 gene page |
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HSPB7 represses formation of abnormal actin bundles independent of Lmod2
Show the 1 phenotype image(s) involving this allele.
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Mutant Cell Lines: |
10985A-B9, 10985A-C6, 10985A-F1, 10985B-B4, 10985B-C3, 10985B-C11, 10985B-G6 |
Germline Transmission: |
Earliest citation of germline transmission:
J:227272
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Parent Cell Line: |
VGB6 (ES Cell)
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Strain of Origin: |
C57BL/6NTac
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Project Collection: |
KOMP-Regeneron
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
Vector: ZEN-Ub1
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Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 7346bp between positions 24597866-24605211 of Chromosome 6 (Build GRCm39). The entire gene starting at the translational start site and ending at the translational stop site, was replaced with the lacZ reporter cassette. Western blot confirmed complete loss of protein in the left ventricle.
(J:136110, J:227272)
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View phenotypes and curated references for all genotypes (concatenated display).
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Original: |
J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008; |
All: |
5 reference(s) |
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