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Gnb3tm1(KOMP)Vlcg
Targeted Allele Detail
Nomenclature
Symbol: Gnb3tm1(KOMP)Vlcg
Name: guanine nucleotide binding protein (G protein), beta 3; targeted mutation 1, Velocigene
MGI ID: MGI:3812642
Synonyms: Gnb3tm1Vlcg
Gene: Gnb3  Location: Chr6:124834240-124840275 bp, - strand  Genetic Position: Chr6, 59.17 cM
Mutation
origin
Mutant Cell Lines:  10605A-A7, 10605A-A8, 10605A-B1, 10605A-B2, 10605A-E6, 10605A-G11 (Velocigene)
Germline Transmission:  Earliest citation of germline transmission: J:187720
Parent Cell Line:  VGB6 (ES Cell)
Strain of Origin:  C57BL/6NTac
Project Collection: KOMP-Regeneron
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1
 
Mutation detailsThe insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 5082bp between positions 124784654-124789735 of Chromosome 6 (Genome Build37). Western blot analysis confirmed the absence of protein expression in retina. (J:136110, J:187720)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 1 line available
Carrying any Gnb3 Mutation:  4 strains or lines available
Notes
No mutant cell line is specified in J:187720.

References
Original:  J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/20/2015
MGI 5.21
The Jackson Laboratory