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Gnb3tm1(KOMP)Vlcg
Targeted Allele Detail
Summary
Symbol: Gnb3tm1(KOMP)Vlcg
Name: guanine nucleotide binding protein (G protein), beta 3; targeted mutation 1, Velocigene
MGI ID: MGI:3812642
Synonyms: Gnb3tm1Vlcg
Gene: Gnb3  Location: Chr6:124811203-124817238 bp, - strand  Genetic Position: Chr6, 59.17 cM
Alliance: Gnb3tm1(KOMP)Vlcg page
IMPC: Gnb3 gene page
Mutation
origin
Mutant Cell Lines:  10605A-A7, 10605A-A8, 10605A-B1, 10605A-B2, 10605A-E6, 10605A-G11
Germline Transmission:  Earliest citation of germline transmission: J:187720
Parent Cell Line:  VGB6 (ES Cell)
Strain of Origin:  C57BL/6NTac
Project Collection: KOMP-Regeneron
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1
 
Mutation detailsThe insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 5082bp between positions 124811599-124816680 of Chromosome 6 (Build GRCm39). Western blot analysis confirmed the absence of protein expression in retina. (J:136110, J:187720)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 1 line available
Carrying any Gnb3 Mutation:  23 strains or lines available
Notes
No mutant cell line is specified in J:187720.
References
Original:  J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008;
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory