Slc5a8^tm1Boet
Targeted Allele Detail

Summary

• Symbol: Slc5a8^tm1Boet
• Name: solute carrier family 5 (iodide transporter), member 8; targeted mutation 1, Thomas Boettger
• MGI ID: MGI:3811497
• Gene: Slc5a8 Location: Chr10:88721854-88765377 bp, + strand Genetic Position: Chr10, 44.34 cM
• Alliance: Slc5a8^tm1Boet page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:139883
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed neo cassette was inserted upstream of exon 4 and an additional loxP site was inserted downstream of exon 5. (J:139883)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc5a8 Mutation: 42 strains or lines available

References

• Original: J:139883 Frank H, et al., Lactaturia and loss of sodium-dependent lactate uptake in the colon of SLC5A8-deficient mice. J Biol Chem. 2008 Sep 5;283(36):24729-37
• All: 1 reference(s)