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Targeted Allele Detail
Symbol: Edil3tm1Gpy
Name: EGF-like repeats and discoidin I-like domains 3; targeted mutation 1, George P Yang
MGI ID: MGI:3811078
Synonyms: Del1-LacZ
Gene: Edil3  Location: Chr13:88821472-89323223 bp, + strand  Genetic Position: Chr13, 45.3 cM, cytoband C3
Germline Transmission:  Earliest citation of germline transmission: J:139931
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA 2.1 kb thymidine kinase cassette, a 1.6 kb neo cassette, and a 3.6 kb lacZ cassette were inserted into exon 1 disrtupting the first ATG codon. The authors state that this is a null mutation. (J:139931)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Edil3 Mutation:  6 strains or lines available
Original:  J:139931 Hsu GP, et al., Increased rate of hair regrowth in mice with constitutive overexpression of Del1. J Surg Res. 2008 May 1;146(1):73-80
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.14
The Jackson Laboratory