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Ptk2btm1Okig
Targeted Allele Detail
Nomenclature
Symbol: Ptk2btm1Okig
Name: PTK2 protein tyrosine kinase 2 beta; targeted mutation 1, Mitsuhiko Okigaki
MGI ID: MGI:3811004
Gene: Ptk2b  Location: Chr14:66153257-66281052 bp, - strand  Genetic Position: Chr14, 34.36 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:139849
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA neomycin selection cassette was inserted in an unspecified exon. Absence of protein product was confirmed immunologically. (J:139849)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ptk2b Mutation:  3 strains or lines available
Notes
ES cells of WW strain were used.
References
Original:  J:139849 Matsui A, et al., Central role of calcium-dependent tyrosine kinase PYK2 in endothelial nitric oxide synthase-mediated angiogenic response and vascular function. Circulation. 2007 Aug 28;116(9):1041-51
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory