Tg(Fabp7-cre,-lacZ)3Gtm
Transgene Detail
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Symbol: |
Tg(Fabp7-cre,-lacZ)3Gtm |
Name: |
transgene insertion 3, David H Gutmann |
MGI ID: |
MGI:3810647 |
Synonyms: |
BLBP-cre, BLBP-cre-lacZ |
Transgene: |
Tg(Fabp7-cre,-lacZ)3Gtm Location: unknown
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Alliance: |
Tg(Fabp7-cre,-lacZ)3Gtm page
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Strain of Origin: |
C57BL/6 x CBA
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Transgene Type: |
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Transgenic (Recombinase) |
Mutation: |
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Insertion
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Tg(Fabp7-cre,-lacZ)3Gtm expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Fabp7 (MGI:101916) |
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Mutation details: A 1.6 kb fragment of murine Fabp7 drives expression of a nuclear targeted cre. The transgene also contains and IRES-lacZ sequence. LacZ expression is seen in the ventricular region of the spinal cord and in the hindbrain at E9.5, in thedorsal portion of the rostral neuroepithelium and in the midbrain at E10.5, extending into the ventricular/subventricular regions of the brain by E12.5, and in the ependymal cell layer of the ventricle with distinct labeling in the subventricular zone in young adults. No expression is detected in other organ systems. Three lines were generated with lines 2 and 3 having identical expression patterns.
(J:139866)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Fabp7
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:139866 Hegedus B, et al., Neurofibromatosis-1 regulates neuronal and glial cell differentiation from neuroglial progenitors in vivo by both cAMP- and Ras-dependent mechanisms. Cell Stem Cell. 2007 Oct 11;1(4):443-57 |
All: |
21 reference(s) |
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