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Tg(Fabp7-cre)2Gtm
Transgene Detail
Nomenclature
Symbol: Tg(Fabp7-cre)2Gtm
Name: transgene insertion 2, David H Gutmann
MGI ID: MGI:3810647
Synonyms: BLBP-cre, BLBP-cre-lacZ
Transgene: Tg(Fabp7-cre)2Gtm  Location: unknown  
Transgene
origin
Strain of Origin:  Not Applicable
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsA 1.6 kb fragment of murine Fabp7 drives expression of a nuclear targeted cre. The transgene also contains and IRES-lacZ sequence. LacZ expression is seen in the ventricular region of the spinal cord and in the hindbrain at E9.5, in thedorsal portion of the rostral neuroepithelium and in the midbrain at E10.5, extending into the ventricular/subventricular regions of the brain by E12.5, and in the ependymal cell layer of the ventricle with distinct labeling in the subventricular zone in young adults. No expression is detected in other organ systems. Three lines were generated with lines 2 and 3 having identical expression patterns. (J:139866)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Fabp7     Summary of all recombinase alleles driven by Fabp7.
 

Phenotypes
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Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:139866 Hegedus B, et al., Neurofibromatosis-1 regulates neuronal and glial cell differentiation from neuroglial progenitors in vivo by both cAMP- and Ras-dependent mechanisms. Cell Stem Cell. 2007 Oct 11;1(4):443-57
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory