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Sfrp2tm1Ktas
Targeted Allele Detail
Nomenclature
Symbol: Sfrp2tm1Ktas
Name: secreted frizzled-related protein 2; targeted mutation 1, Kei Tashiro
MGI ID: MGI:3810257
Gene: Sfrp2  Location: Chr3:83766321-83774316 bp, + strand  Genetic Position: Chr3, 37.37 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:138805
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 was replaced with a neo cassette via homologous recombination. RT-PCR and in situ hybridization analysis confirmed the absence of transcript and protein in homozygotes. (J:138805)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 22 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sfrp2 Mutation:  15 strains or lines available
References
Original:  J:138805 Ikegawa M, et al., Syndactyly and preaxial synpolydactyly in the single Sfrp2 deleted mutant mice. Dev Dyn. 2008 Sep;237(9):2506-17
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory