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Targeted Allele Detail
Symbol: Suv420h2tm1.1Jnw
Name: suppressor of variegation 4-20 homolog 2 (Drosophila); targeted mutation 1.1, Thomas Jenuwein
MGI ID: MGI:3810079
Gene: Suv420h2  Location: Chr7:4740115-4747514 bp, + strand  Genetic Position: Chr7, 2.74 cM
Small size of Suv420h1tm1.1Jnw/Suv420h1tm1.1Jnw and Suv420h1tm1.1Jnw/Suv420h1tm1.1Jnw Suv420h2tm1.1Jnw/Suv420h2tm1.1Jnw mice

Show the 1 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:139510
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Germ line, cre mediated recombination was used to remove exons 1 through 5. (J:139510)
Generation of the Suv420h2tm1Jnw and Suv420h2tm1.1Jnw alleles
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Suv420h2 Mutation:  15 strains or lines available
Original:  J:139510 Schotta G, et al., A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse. Genes Dev. 2008 Aug 1;22(15):2048-61
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.05
The Jackson Laboratory