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Suv420h2tm1.1Jnw
Targeted Allele Detail
Nomenclature
Symbol: Suv420h2tm1.1Jnw
Name: suppressor of variegation 4-20 homolog 2 (Drosophila); targeted mutation 1.1, Thomas Jenuwein
MGI ID: MGI:3810079
Gene: Suv420h2  Location: Chr7:4740115-4747514 bp, + strand  Genetic Position: Chr7, 2.74 cM
Small size of Suv420h1tm1.1Jnw/Suv420h1tm1.1Jnw and Suv420h1tm1.1Jnw/Suv420h1tm1.1Jnw Suv420h2tm1.1Jnw/Suv420h2tm1.1Jnw mice

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:139510
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Germ line, cre mediated recombination was used to remove exons 1 through 5. (J:139510)
Generation of the Suv420h2tm1Jnw and Suv420h2tm1.1Jnw alleles
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Suv420h2 Mutation:  15 strains or lines available
References
Original:  J:139510 Schotta G, et al., A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse. Genes Dev. 2008 Aug 1;22(15):2048-61
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory