Sh2d4atm1Pdk
Targeted Allele Detail
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Symbol: |
Sh2d4atm1Pdk |
Name: |
SH2 domain containing 4A; targeted mutation 1, Philip D King |
MGI ID: |
MGI:3809251 |
Gene: |
Sh2d4a Location: Chr8:68729219-68800351 bp, + strand Genetic Position: Chr8, 33.76 cM, cytoband C1
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Alliance: |
Sh2d4atm1Pdk page
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Germline Transmission: |
Earliest citation of germline transmission:
J:139245
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Parent Cell Line: |
Bruce 4 (ES Cell)
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Strain of Origin: |
B6.Cg-Thy1a
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: LoxP sites were inserted around exon 8 and a frt-flanked neomycin cassette was inserted in the intronic sequence between exons 8 and 9. Progeny were crossed with transgenic mice expressing Flp-recombinase in order to remove the neomycin resistance cassette.
(J:139245)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Sh2d4a Mutation: |
21 strains or lines available
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Original: |
J:139245 Lapinski PE, et al., Genetic analysis of SH2D4A, a novel adapter protein related to T cell-specific adapter and adapter protein in lymphocytes of unknown function, reveals a redundant function in T cells. J Immunol. 2008 Aug 1;181(3):2019-27 |
All: |
1 reference(s) |
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